Brothers the intersection of mouth and disease become infant and pre-school children cause death arch-criminal repeatly Vaccine appearance needs time

Brothers the intersection of mouth and disease become infant and pre-school children cause death arch-criminal repeatly Vaccine appearance needs time
Brothers the intersection of mouth and disease become infant and pre-school children cause death arch-criminal repeatly Vaccine appearance needs time
The mouths of brothers are ill: Arrest " attack baby's hands " The slight virus infective disease of a kind of script, become lethal arch-criminals of infant and pre-school children in recent years but repeatedly, brothers' mouth disease is listed in legal infectious disease for three years, namely the first of leaping to class-C infectious disease and having illness coming on. In its being high to send machine that situation appear, enter, research and develop among the the procedure already to vaccine of disease this The reporter / the Wang 's is quick By May 4, our country has already reported to 427278 ill cases of mouths of brothers totally, increased by 41.51% compared with the same period of 2009, 5454 serious diseases among them, 260 cases of death. This it is the intersection of Ministry of Public Health and disease that prevent and cotrol DongLou Xiao, Deputy Bureau Director of office, " prevented and cured brothers' mouth disease in hold a few days ago, it is healthy to protect children " The media links up the newest data revealed at the meeting. Peak period when brothers' mouth disease has illness coming on is generally in May - July. Epidemiology chief scientist Zeng Guang of Center for Disease Prevention and Control of China says, in cases lacks valid treatment means and vaccine and has not succeeded in developing yet, in the will it be some time future, brothers the intersection of mouth and disease in high to take place the situation also. On May 13, with the affirmation of second brothers' mouth disease death case of this year of Beijing, Beijing Municipal Health Bureau unites Municipal Education Commission and gives notice, proposes that once serious disease or death case appears, relevant nurseries and kindergartens organizations suspend classes for 10 days. The virus infective disease not paid attention to of each, after listing in legal infectious disease for two years, namely have illness coming on and count the first as class-C infectious disease rapidly - -Brothers' mouth disease, this kind occurs frequently to break out and cause the death case and cause the extensive concern in all parts constantly in the cause of disease of infection of the infant and pre-school children under the age of 5 in recent years. The diversified one " The virus table " The mouths of brothers are ill to regard bleb of positions such as hands of infant and pre-school children, foot, oral cavity,etc. as the main characteristic, and therefore gain the name. Usually, it is not paid attention to the medical circle very much as dept. of dermatology and case that the pediatrics distributes. Though, the medical book records it " can also cause serious complications such as myocarditis, lung edema, meningitis,etc.. " In March of 2008, take place and break out to lead to the fact at least on mouths of brothers of Fuyang of Anhui 23 children die, thus cause the general attention. In May of the same year, Ministry of Public Health listed it in infectious disease and prevented and cured the class-C infectious disease that France stipulated and paid and managed. Have data reveal brothers prevailing range and scale, mouth of disease really expand to some extent in recent years already, mortality is rising too. The biological chief of research institute of the etiology of the Chinese Academy of Medical Sciences has strange money to tell the " Chinese Newsweek " reporter, "brothers the intersection of mouth and disease like other infectious diseases, have large to prevail and prevail stage while being little, can break out with year and season. And the intersection of brothers and the intersection of mouth and disease list legal the intersection of infectious disease and catalogue in recently, at all levels medical treatment and disease accuse of organization begin the situation appear in the newspaper according to the regulation to having illness coming on, therefore, the onset data unavoidably rise suddenly. " Study carefully it break out reason, gold strange to think, have economic development, environmental climate, life style, the intersection of social structure and the intersection of person who change and factors in many aspects, and still lack the foundation and control the data at present, every area can't treat as the same either. "Brothers the intersection of mouth and disease infect prevailing overall the intersection of disposition and condition, the intersection of virus and where one is popular district, distribute etc., still remain to study the conclusion in aetiology and epidemiology, under the circumstances that China's present disease accuses of the system, there are no relatively intact monitoring data. " Is it pathogenic to accuse of by table information disease,it initiate brothers the viruses intestinal of the mouths disease not to 20 multi-type at China (type) ,Among them with strange the intersection of virus and Model A16 (CoxA16) Sa Ke With the intestinal virus 71 type (EV71) Most common, infective to stronger than other type other virus. In monitoring samples in all parts, clinical serious disease patient with nervous system symptom, rely mainly on the fact that EV71 virus is infected. According to the strange analysis of gold, every area mostly rely mainly on the fact that the one kind type other virus among them prevail, two kinds of virus exist in the few area to prevail at the same time. For example, in some and popular in Shandong in 2007, 70% of the cases are that EV71 infect, it accounts for about 20% of the total number for CoxA16 to infect; Anhui Fuyang break out, rely mainly on the fact that EV71 infected too while being prevailing 2008; Mainly EV71 will prevail in Yunnan Province in 2009, will turn a case infected into a CoxA16 type and account for 57% in 2010. The increase having illness coming on in all parts with the mouths of brothers, from 2008, Ministry of Public Health has printed and distributed " guide of making a diagnosis of to the mouths of brothers " for three years in succession, require the health authorities at all levels to strengthen the epidemic situation and monitor the report. " the strange one " Infectious disease, before breaking out prevailingly, China lack the intersection of rival and the intersection of foot and research, mouth of disease, rarely seen and relevant scientific findings. In 1957, the first brothers' mouth disease case was found in Canada; In the seventies of last century, EV71 virus was first affirmation in U.S.A.. Near and from 10 to 20, brothers the intersection of mouth and disease all district had to break out different scale in world, include successively prevailing in Taiwan, Hong Kong area and Malaysia. "There are no national boundaries in infectious disease, the prevalence of China Mainland is the thing sooner or later. " Qi Jin say " as to other more harmful infectious diseases, brothers the intersection of mouth and disease start in domestic research work later relatively really. " 2008, Fuyang brothers disease large break out, mouth have, Ministry of Public Health organize the intersection of China and Center for Disease Prevention and Control, Chinese Academy of Medical Sciences expert of unit, the special topic has been discussed to strengthen the technological frame that a disease of brothers prevents and cures and studies. "The government begins to pay attention to, can not be invested a large amount of reasearch funds and but can't be avoided either to and treat the question on in clinical diagnosis. " Gold strange to think brothers the intersection of mouth and disease prevail among the three year, expose the intersection of Chinese and medical organization especially at the basic level medical treatment treat deficiency of terms, "view from the point of surveying and studying the situation, the medicine of some villages, basic understanding of the health station of village and town even at county level the intersection of hospital rival and the intersection of foot and the intersection of mouth and disease are insufficient, also lack the clinical technology of making a diagnosis and giving treatment. " In basic unit, brothers the intersection of mouth and main foundation of disease signify clinically to diagnose, the pathogenic virus is difficult to distinguish. Cause the intestinal virus of brothers' mouth disease to include over 10 serum types, the hospital at the basic level lacks fast, simple and convenient detection means. Jin Qi says, " the fast detection law of some intestinal virus needs the laboratory of special terms, it is unripe that the villages and towns, first class medical organization of community do the condition measured fast, can not diagnose the laboratory to every one either. " In addition at the intersection of rival and the intersection of foot and treatment, mouth of disease, still in order to relieve symptom, reduce, amalgamate emergence of disease for main fact at present, lack peculiar treatment means. With comparing to antibiotic of the bacterial infection, the function against virus medicine is very limited too. Brothers the intersection of mouth and disease like other virus infective diseases, have certain " the limit since " fortunately ,The patient with slight symptom can recover without treatment in about one week. Gold is strange to think, virus is not able to bear medicines, makes a variation or the enhanced evidence of virulence at present, but The reason why brothers' disease fond of salty food, death case increase, is lacking the effective antiviral medicine, "at the clinic, course of disease change fast and recessive symptom to cause main causes of death. " It is introduced, the course of disease of the intersection of brothers and the intersection of mouth and disease is changed perhaps very fast, EV71 serious disease infects and presents nervous system symptom within 10 hours, have increased the difficulty treated and cured. In addition some case might not have typical sign in initial stage, for example die in the case in 19 that Guangxi take place will it be April this year, have not mostly presented rash. Wait for vaccine brothers 2 to 7 day in incubation period in disease in mouth, infect source, include patient and recessive the infeted, mainly spread through routes such as the digestive tract, respiratory tract and keeping in close touch,etc.. Have only thought, in a situation that diagnosis, therapeutic method have been limited at present, prevent the links which become key. Have only told the " Chinese Newsweek " reporter, mainly carry on disease control through the means of the general behavior at present, such as sanitation and hygiene, isolating, reducing to keep in touch, propagating and educating, going to a doctor etc. in time, he thinks, " the most ideal measure is to control the prevalence of disease through vaccine. " In fact, scientific circles is set about researching and developing ill specific vaccine of mouths of brothers used for children since 2008. Beijing department revitalize the intersection of biologicals and Co., Ltd. already until first declare the intersection of brothers and the intersection of mouth and the intersection of disease and relevant the intersection of research and development and event of vaccine at home, the Model EV71 virus that they developed deactivates vaccine and already supervises the administration bureau applying to enter registration of clinical trial to Beijing medicines on December 24 of 2009. It if you can't register, examine and approve through after,last clinical researches the first stage of vaccine. According to the introduction of relevant person in charge, vaccine needs to pass three clinical trials at least, every the first stage of result needs to prove that examine and approve through the strictness of Bureau of Drugs Supervision. Zeng Guang says, every vaccine should be responsible for life. He estimates, it has a relatively longer course that used in the human body to specific vaccine of brothers' mouth disease.


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