A disease of brothers deactivates the first stage of clinical trial of vaccine to finish

A disease of brothers deactivates the first stage of clinical trial of vaccine to finish
A disease of brothers deactivates the first stage of clinical trial of vaccine to finish
It is reported ' Old and graceful dawn the people Yue, king of reporter,) The department of Beijing revitalizes biologicals Co., Ltd. to announce on May 25, the 71 type intestinal virus researched and developed independently by this company (EV71, it is a mouthful of disease and main pathogenic virus of brothers) It is blind to deactivate the first stage of clinical test data of vaccine and take off Beijing. Vaccine security observation and preliminary original result of study of immunity reveal, vaccine has better security and can produce the good immunity to reply. EV71 that this company develops deactivates vaccine and obtains national food medicines to supervise the clinical trial official written reply of the administration bureau last December, and start the first stage of clinical trial in Center for Disease Prevention and Control of the county of Mengshan, Wuzhou of the Guangxi Zhuang Autonomous Region formally on the 31st of that month. It is reported, the first stage of clinical trial takes single centre, blind law, placebo at random to contrast the way, choose to include adult, children and infant and pre-school children amount to 168 experimenters, it is original in order to appraise EV71 to deactivate vaccine security and preliminary immunity in different crowds. In the first stage of clinical trial, finish adult's group (18 years old and the above) together on December 31, 2010 - February 11, 2011 3 stitches of vaccine inoculated, finished children's group (3 years old - 11 years old) on February 20 - April 28, 2011 3 stitches of vaccine inoculated, finished infant and pre-school children's group (6 months - 35 months old) on February 27 - May 16, 2011 3 stitches of vaccine inoculate. The clinical test result reveals, there is not statistics difference to inoculate different dosage vaccine groups and bad reaction of the placebo control group, see, increase, inoculate the intersection of needle and time, increase, inoculate dosage, cause the intersection of bad reaction and the intersection of incidence and raise and the intersection of bad reaction and phenomenon that rank increases; Observe, clinical auxiliary examination under the blind attitude through clinical medicine ' Electrocardiogram, blood pressure, heart rate,etc.) And laboratory check ' Blood routine, blood biochemistry, urine routine) Wait, vaccine of this test has not seen the serious bad reaction, this indicates it is good that EV71 deactivates vaccine security and tolerance. Preliminary getting original immunity result brief on, inoculate 2 stitch can it produces better immunity to be getting former behind the vaccine. It is reported, the second stage of clinical trial will be started in one month - 2 months.


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