My scientist heads the list of signers in the human protein group and studies and obtains breakthrough progress

My scientist heads the list of signers in the human protein group and studies and obtains breakthrough progress
My scientist heads the list of signers in the human protein group and studies and obtains breakthrough progress
Reporter's money shakes Rong reporter Wu ZhiJun, Shen JiFei news from Beijing on October 20 " who'd have thought of that, people and mouse, the genome have the same 99%, but the appearance is as far apart as heaven and earth, where is the secret? In that various protein group thoroughly, it is numerous and complicated and colourful that it is exactly that it has brought up different lives. " Great meaning in which director of group of protein of Beijing research center academician He FuChu has explained group studies protein like this. In October of this year, the research center of group of protein of Beijing is just established for five years. Originally, He Fu suggested establishing " the human liver protein group study the plan " at the international conference at the beginning When, that expected is to look for and treat the gold key of hepatopathy for this hepatitis big country of ours. One year later, China becomes taking the lead in the country of this plan, He Fu serves as a president for the first time. It is reported, the research is complicated and arduous, and need hundreds of millions of of fund, even the global scientist works in concert, also takes several dozen years. June of 2004, in order to combine the domestic and foreign superior resources, by the military academy of medical sciences, Chinese Academy of Sciences, Chinese Academy of Medical Sciences, group, Beijing biotechnology and new medical industry promote the centre to jointly establish the research center of group of protein of Beijing in Tsing-Hua University, Peking University, river. So far, the centre has already attracted altogether thousands of outstanding scientists of 18 countries, more than 100 laboratories in the whole world to participate in this research work. In five years, the centre made many great achievements. It is appraised that they succeeded in human liver protein more than 13000 kinds; Construct the largest scale in the world, contain more than 3480 to the high network chart that can believe liver protein interaction, adjust and control the molecule in the signal thorough fare where find 58 kinds of potential liver disease candidate gene, 92 kinds of potential liver phenotype genes and 260 multi-type is new; Have set up the human organ protein group's database of the first system in the world, quoted by a plurality of international important protein group's databases and important scientific papers. In addition, the centre has also found fatty liver, hepatocyte virus infecting, canceration and shifting relevant protein mark group, potential medicine target and drug candidate; Have announced function mechanism,etc. that the bone forms and is shouldered and adjusted and controlled member and steady state of bone quantity in the organism while adjusting and controlling; Have found relevant exchanging the sense gene of complicated disease such as one batch and hepatocarcinoma, nose of pyemiapyaemia and swallowing cancer. Discovery these, one that is for above-mentioned disease prevent from in early days and early-warning, risk predict and individual's medical treatment lay the solid foundation.


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