Our country is expected to find the disease molecule target of first silver bits to the medicine

Our country is expected to find the disease molecule target of first silver bits to the medicine
Our country is expected to find the disease molecule target of first silver bits to the medicine
It is reported ' Reporter Hu DeRong) King of Shanghai Communications University medical college great Professor Lin is on the basis of cooperating with researcher of Germany Ulm university, it develops a name to be little the intersection of member and natural work compound of AKBA, compound these is expected to become new medicine of the intersection of treatment and silver the intersection of bits and disease, the relevant research thesis is issued on the international authoritative " amynologic magazine " recently. " natural rheumatism learnt to summarize " will develop and classify as and study the light spot a few days ago, think AKBA may be used for treating the other chronic inflammation diseases that relate with nuclear transcription factor NF-kappaB. Silver the intersection of bits and disease ' Commonly called as psoriasis) It is a kind of common chronic dermatosis, apt to recur, it is difficult to effect a radical cure, the morbidity in our country is about 0.123%. Because have a large population, in our country, the disease patient of the silver bits is a very big colony. At clinic, silver the intersection of bits and disease considered to be the thing a kind of CD4 positive T cell lies between one's own immune disease led. But increasingly much research indicate macrophage whether silver the intersection of bits and disease have illness coming on the intersection of cell and important source of factor in front of the a lot of inflammation under course. Have, study, show silver the intersection of bits and morbidity and skin of disease decrease to lie between plain - 23 (IL-23)s in vain position already in the world And the activation of nuclear transcription factor NF-kappaB is closely related. Under study for action, Professor Wang HongLin,etc., through setting up animal's model, develops the little member AKBA of natural activity who inhibits the activatory nuclear transcription factor NF-kappaB, then use the intersection of lipid and body as target to give medicine carrier, input in the macrophage and reach to silver the intersection of bits and the intersection of disease and little the intersection of mouse and the intersection of member and target to the result of treatment. AKBA is the active extracts of a kind of natural herbaceous, the target tropism is strong, and the raw materials source are extensive, cheap, making lotion sides, oral tablets or parenteral solution can obviously improve symptom of silver the intersection of bits and disease, reduce the patient's pain.


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