Our country proposes early rheumatoid and arthritis and diagnoses the new standard

Our country proposes early rheumatoid and arthritis and diagnoses the new standard
Our country proposes early rheumatoid and arthritis and diagnoses the new standard
It is reported ' Reporter Wang Dan) As the country " Eleven five " One of the science and technology support plans " Rheumatoid arthritis (RA) Early diagnostic method, therapeutic research " A part,it is first RA early periods based on Chinese crowd's characteristic take shape already tentatively at present diagnostic standards categorised. In the 16th national rheumatism society that is held recently discusses, one of the persons in charge of this seminar, rheumatism immune department's Deputy Director Su Yin of the People's Hospital of Peking University say, this standard has overcome the traditional criteria for classification to diagnose the insensitive shortcoming to early RA, to to examine, manage, reduce the intersection of limb and the intersection of deformity and incidence, raise the intersection of patient and the intersection of life and quality,etc., have important meanings early early RA. This subject is participated in finishing together by the immune department of rheumatism of hospital of 12 of the first, second and third of the whole country, include in 850 patients altogether, the age is over 16, and the course of disease is smaller than one year while entering the group. Pass, follow up a case by regular visits to 1 year, clinical manifestation, the intersection of laboratory and index and image in patient learn the intersection of person who check and statistical analysis of index, confirm finally: Stiff in the morning time is greater than an hour, add up to more than 3 joint districts, hand joints and is given much trouble, the symmetrical joint is given much trouble, it is unusual to be given much trouble the joint X-ray, resist ring citrulline peptide (CCP) Positive, the rheumatoid factor is positive, diagnose the index for the early RA new classification. Rheumatoid and arthritis are a kind of one's own immune disease with unidentified cause of disease, our country nearly has 5 million patients at present. It is often shown as the symmetry little joint swelling and aching and activity is limited that this disease is early, the patient not normal and therapeutic will develop into joint deformity, limb and disable finally. Yin Su say commonly used RA to learn, make by the intersection of U.S.A. and rheumatism 1987 in categorised diagnostic standard at being at present clinical, because the course of disease of patients included in is relatively long while making this standard, it was about 7.8 on average, the sensitiveness that this standard diagnoses to early RA is relatively bad. Later, U.S.A. rheumatism learn, resist the intersection of rheumatism and alliance, recommend new the intersection of rheumatoid and the intersection of arthritis and criteria for classification together with Europe, but study to reveal, this standard is apt to cause the excessive diagnosis (false positive rate of early RA to be high) . The expert says, compared with traditional standard, RA that our country puts forward diagnoses the new standard not merely facilitates memory in early days, and can obviously improve the sensitiveness diagnosed ' Increase from 62% to 87%) ,The specificity has not changed ' 90% and 84%) . As to the thing that whether this new categorised diagnostic standard could replace the traditional standard, Su Yin says frankly, need in go on the large-scale case prove while being clinical also.


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