The scientific research personnel of our country find 71 new antibacterial peptide families

The scientific research personnel of our country find 71 new antibacterial peptide families
The scientific research personnel of our country find 71 new antibacterial peptide families
Special despatch of November 15 of www.xinhuanet.com Kunming (reporter Li Meng) The reporter learns from Ins of animal of Kunming,Academia Sinica, scientific research personnel recognise 728 different antibacterial peptide molecules of maturity from the discredited frog's skin secretion. These antibacterial peptides are divided into 97 families, among them 71 families are the first name. The animal Assistant Researcher of research institute Li WenHui in Kunming of Chinese Academy of Sciences who participates in this research project introduces, antibacterial peptide molecule of the new discovery will offer a large number of new templates for the fact that the new antibacterial peptide medicine is designed, contribute to developing the new antibacterial medicine. Antibacterial peptide is distributed over the animals and plants in the body extensively, it is the important part of the natural immune system of living beings. In recent years, with the using in a large amount of traditional antibiotic, it is able to bear the bacterial strain of medicine to present various on clinic, the new antibacterial medicine utilizing antibacterial peptide to research and develop has poisonous small, difficult to produce and is able to bear advantages such as nature,etc. side effects. Amphibian animal animal's skin has been the resource treasure-house in family's eyes of the science all the time, contain active polypeptide of a large number of unknown functions in its secretion. The discredited frog of frog's family belongs to and occupies important position in the evolution of the whole amphibian animal animal, it is importance carrying out the transition group from real frogs to frog evolution of water of animal of frog's family. Nearly there are 20 kinds of discredited frogs in the world, among them China nearly distributes 13 kinds. It is introduced, on two years, the model of animal of the Chinese Academy of Sciences and key laboratory " biological toxin and mankind's disease discipline group " of mankind's disease mechanism Researchers gather 9 kinds of characterized discredited frogs to China from Yunnan, Guizhou, Sichuan and other places, study and genomics means through the protein group, recognise 728 different antibacterial peptide molecules of maturity from these 9 kinds of discredited frog's skin secretion, among them 662 are first reports, these antibacterial peptides have taken known 30 against fungus peptide in the nature at present. These antibacterial peptides are divided into 97 families, among them 71 families are the first name. This research still shows, the discredited frog may be antibacterial peptide variety most abundant species in the nature, proved the same antibacterial peptide will be distributed in a large amount on discredited frog of different kinds at the same time. It is reported research project this get the intersection of country and " the 973 " Subsidy in projects such as plan, national natural science fund,etc..


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