The scientist of our country finds leprosy and exchanges the sense gene

The scientist of our country finds leprosy and exchanges the sense gene
The scientist of our country finds leprosy and exchanges the sense gene
It is reported ' Reporter Zhang ZhongTian) Shandong Government holds the news briefing and announces on December 17: Units such as Shandong dermatosis research institute of prevention and treatment of venereal diseases,etc., adopt the international latest related analytical method of the whole genome, through the study on 11400 leprosy patients and persons who contrast healthily, have found exchanging the sense gene of 7 pieces of leprosy, and prove that has common exchanging the sense gene to leprosy in different nationalities of China. The internationally famous academic periodical " medical magazine of New England " issued this research results online on the same day. This research is a research group led by the dermatosis researcher of research institute Zhang FuRen of prevention and treatment of venereal diseases in Shandong, unite the one of institute of internal medicine of medical university of Anhui and learn military affairs in professor's group and Singapore state-run genetic Professor Liu Jianjun of research institute group, utilize the southern research center of the national human genome and the whole genome of medical university of Anhui to be concerned with experiment platform of analysis and analytical technique, it is finished that it lasts 3 years. Study the case sample used, the prophylactico-therapeutic institutions of more than 100 of leprosy from Shandong, Jiangsu, Yunnan and Anhui. The disease patient drops by a wide margin in the world now through the integrated control of decades, leprosy. But because lacked the first class precautionary measures, had illness coming on newly people's quantity was not obviously reduced, more than 200,000 examples are reported to the case newly every year in the whole world, our country has new case reports of 1600 examples every year. By the end of 2008, nearly 300 counties are still in the prevailing state of leprosy in our country, and the leprosy fungus still can't be trained outside the body so far, has not prevented vaccine of leprosy either. According to the introduction of researcher Zhang FuRen, though exchanging the gene studies of the sense at leprosy of scientist all around the world has carried on untiring efforts, find generally approved to exchange the sense gene yet. Shandong, Anhui and Singaporean scientist last 3 years these 7 pieces of leprosy that discover exchange the sense gene, have participated in the organism from discerning and presenting dealing with to the antigen, the cell factor is regulated and the immune cell signal is transferred to inflammation and immune course of leading etc., the variation of these genes is closely linked to having illness coming on in the mechanism. And these exchange the intersection of sense and gene exist in the intersection of the Han nationality and leper, prove in leper, ethnic minority of Yunnan. It is reported, the related analysis of the whole genome finds the research results of exchanging sense gene of leprosy, have important scientific value in the fields of prevention and cure of disease and biomedical research.


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