The scientist of our country finds hepatitis B and virus survive in the mechanism newly
The scientist of our country finds hepatitis B and virus survive in the mechanism newly
It is reported ' Reporter Li TianShu) A few days ago, Chinese Academy of Sciences the intersection of Shanghai and the intersection of life and the intersection of research institute and biochemistry and the intersection of cell and biological the intersection of research institute and Zhao admire one 30 jin of latest research of seminar, have found a kind of new existence mechanism of B-mode hepatitis virus. The relevant achievement is issued on the " the liver will be studied " magazine published in the near future. Hepatitis B and virus (HBV) It not only can cause urgent, chronic hepatitis to infect, but also and the emergence of liver cirrhosis and hepatocarcinoma is closely related with. In the albumen of HBV code, the B-mode hepatitis virus X albumen is considered to participate in the pathologic course of chronic hepatitis B and bring out the most important protein of hepatocarcinoma. Hepatitis B and virus X albumen influence various life activities of the constellation chief cell extensively, including regulating cells withers and dies, inhibits the repair of cells DNAing etc.. Researchers such as Zhao MuJun,etc. have found a new function of the B-mode hepatitis virus X albumen - -Regulate the engulfing by oneself of constellation chief cell. Engulf the existence that can maintain cells when the nutriment of cell lacks by oneself, people beclin1 gene are the gene engulfed by oneself in first induction that is found in the mammal. This seminar finds beclin1 gene is expressed, risen in HBV positive hepatocarcinoma is organized. When they channel the B-mode hepatitis virus X albumen into the liver cancer cell, find the expression level of beclin1 rises, have briefed on the next kind of possible existence mechanism in the hungry environment of the hepatocyte that HBV infects. This discovery has offered the new thinking for the fact that next research HBV is infected with development mechanism happened with hepatocarcinoma.
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