The scientist of our country finds that exchanges the sense gene in vitiligo

The scientist of our country finds that exchanges the sense gene in vitiligo
The scientist of our country finds that exchanges the sense gene in vitiligo
It is reported ' The intersection of reporter and the intersection of reporter and LiHai Yan) set up, Feng June 6, internationally famous academic periodical <> - -It is analysed and researched (GWAS) that the whole genome is related Find that exchanges the sense gene in vitiligo, study to confirm vitiligo is one's own immune disease at the same time. Vitiligo is that a kind of common pigment takes off losing dermatosis, the reason is not clear so far, the patient of our country has already exceeded 10 million. It's time for and recover from illness, take place at face department, the place skin pigment in one's power is totally taken off and lost and presented porcelain white, influence the face seriously. These research adopts the related analysis research approach of the the whole genome, carry on the gene dividing type to nearly 20,000 China the Han nationality, patient of vitiligo of the Uygur nationality and person who contrasts health together, find the gene having illness coming on with vitiligo and is closely related with, including human leucocyte antigen (HLA) in 3 areas 2 piece allele,6 chromosome RNASET2, FGFR1OP and CCR6, size 10 ZMIZ1 of chromosome. The expert points out, HLA gene regulates human immunoreaction, the immune disease of CCR6 and mankind itself is closely related with, ZMIZ1 controls black plain cell development of skin and function, the unusual manifestation of these genes causes the emergence of vitiligo. Zhang XueJun says, all the time opinions vary in the academia in the morbidity mechanism of vitiligo, this research is clear with the strong evidence, it is the main reason that vitiligo has illness coming on that one's own immunity caused by the inherent cause is unusual, this has offered new evidence for announcing the morbidity mechanism of vitiligo in an all-round way. This research still constructs first Asian crowd's vitiligo case - -Contrast the related analysis database of the whole genome, in order to confirm the morbidity mechanism of vitiligo, carrying on prewarning of disease, clinical diagnosis, new medicine development and individual treats and offers according with directly. Research this two enclose institute, enclose institute by medical university by Anhui, Fudan University subsidiary the intersection of Huashan and hospital wait for domestic more thanth unit cooperate, last 5 years, " 863 " in the country Plan, " 973" Finish under the subsidy of the plan and special scientific research fund of Anhui Province.


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