Fire gastric carcinoma to examine early " The blocking action "

Fire gastric carcinoma to examine early " The blocking action "
Fire gastric carcinoma to examine early " The blocking action "
The intersection of staff reporter and good the intersection of special correspondent and Ni Li winter the intersection of reporter and Zhang MiLi Tan Gastric carcinoma is one of our country's morbidity and malignant tumour of higher mortality. Under the background of fact that the basic research has not made the great breakthrough yet, it has a very important realistic meaning in the patient that every point of clinical curative effect is promoted. The reporter knows when Shanghai Communications University medical college subsidiary Rui Jin hospital interview recently, the diagnosing rate in early days of this courtyard of gastric carcinomas is up to about 21% for years, is higher than the average national level (under 10%) notably . This institute also takes the lead in the new technology of making a diagnosis that the warm chemotherapy in the abdominal cavity by stages, in the skill of the clinical pathologic norm inhibited tumour from shifting,etc. before launching the skill at home, make gastric carcinoma patient survival rate up to 44.2% in global 5. "The problem, improving curative effect through meeting while researching and solving clinically is the clinician's duty. " This Professor Zhu ZhengGang, president of institute, explains the job group that he belongs to and devoted to improving the original intention that gastric carcinoma and surgery treat curative effect like this. Diagnose the essential our country is the high taking place area of gastric carcinoma in early days, send more than 400,000 gastric carcinomas newly every year, account for world, have illness coming on 42% of the total number of person. There is no obvious symptom in early days because of gastric carcinoma, are often similar to chronic gastritis, peptic ulcer, so, the later period in most gastric carcinoma patients have already belonged to while making a definite diagnosis of. The patient that the condition develops into this stage, survival rate is only 20% in 5. And if infringe it to the early pathological change of the floor of mucous membrane of stomach, the patient, survival rate can be more than 90% in 5. "Lower the mortality of gastric carcinoma, it is essential to examine and manage early early. This represents clinical level of a hospital, it is the important direction in which cancer prevents and cures in future too. " Zhu ZhengGang says, the medical personnel in Rui Jin hospital has made great efforts in the past 40 years, has followed up a case by regular visits to the high-risk group of gastric carcinoma regularly once, and adopt and focus the new technology of dyeing etc. on micro- inner mirror, fluoro together and find the small cancer cooking stove more, treat in time. In recent years, the diagnosing rate in early days of gastric carcinoma of this institute has already been improved to about 21.6% at present from original 7.6%. Promoting and radically treating a probability patient by stages before the skill is made a definite diagnosis of gastric carcinoma, but the canceration is developed to any extent on earth, usually get pathology and slice the result after performing the operation and have a clear statement. "The tumour pathology after surgery consults the meaning to patient's prognosis and postoperative treatment importantly by stages, but the treatment to the skill and in the skill was helped not big, effective information came too late. " Zhu ZhengGang says, in order to make the patient's healing solution more pointed, this institute takes the lead in the research with phased clinical pathology before launching the skill at home, check, can go on to the patient's canceration by stages before the operation through mirror,etc. in multi-layer spiral CT and supersound. At present, the phased accuracy rate of diagnosis has already been more than 83% before this courtyard of skills. The phased result, can help the doctor to choose to suit the treatment means of patient's condition even more before the skill. It is introduced through make in front of the skill for patient by stages in front of the skill and skill neutralized the postoperative comprehensive healing solution of individualization, can promote the probability that gastric carcinoma effects a radical cure effectively. The relevant research results of this institute have also won the second prize of National Prize for Progress in Science and Technology of 2008. Unite the clinic and realize the gastric carcinoma patient to Rui Jin hospital to see the doctor recently of complex treatment while registering, besides registering for the number of one departments such as gi medicine, oncology department,etc., another one is chosen newly: Unite the clinic. Come from gi medicine, at least 3 different and specialized doctors of surgery, dept. of pathology, clinical nutriology dept., oncology department, 6 relevant clinical departments of radiotherapy department make a diagnosis and give treatment in the same consulting room for the patient. Zhu ZhengGang says, it aims at helping the gastric carcinoma patient to obtain the most suitable comprehensive healing solution to unite the clinic mode, making treats and has an object in view even more. Has taken gastric carcinoma, it's time for it ahead of radiotherapy, or ahead of chemotherapy? Should create the operation a little, or open the belly operation? The patient asks and manages in different departments, the doctor considers from the professional view engaged ined by oneself, perhaps there are different choices. Unite the clinic, reduce the bitterness of rushing about of patients between different departments, help the multi-disciplinary doctor to cooperate together, work out the rational comprehensive healing solution again. Zhu ZhengGang emphasizes, " complex treatment " It is the important transition that tumour treated the idea in recent years. "Tumour treats the mode and already fights from the singles of the single discipline dispersing type toward multi-disciplinary group's cooperating, complex treatment and transforms alone. " Through the union clinic of tumour discipline group of intestines and stomach, can combine different and specialized treatment advantages, thus obtained the optimum healing solution association and improved clinical curative effect. Scientific research is not only to enter the experiment room " while devoted to improving curative effect of gastric carcinoma, the basic work to study pathogenesis of tumour is essential too. " ZhengGang Zhu say " the intersection of pathological change and organization and blood, urine of patient that excise sample,etc. the best scientific research resource behind the operation, can all utilize. " It is reported, this institute has already accumulated various tissue samples of more than 2000 gastric carcinoma patients', researchers are carrying on deeper basic research. At present, has already found 14 candidate genes related to gastric carcinoma, for instance, MPS1 plays a key role in the stomach cancer cell has silks that is split, it has obvious differences in gastric carcinoma and health people's peripheral blood that serum hit the intersection of CF1 and competence. The discovery of the enerprise has important function to the morbidity mechanism that further understands gastric carcinoma. In addition, the gastric carcinoma patient's database is being set up and improved progressively. Researchers attempt to pass the comprehensive analysis to patient's medical history materials, reveal the mysterious veil of gastric carcinoma in terms of family's hereditary history, life history,etc.. Zhu ZhengGang thinks, scientific research is not only to enter the laboratory, works clinically but also have scientific research. An outstanding clinician wants to be good at finding the question in the clinic diagnosis, good at summarizing the experience and lessons, this requires clinicians to pay attention to the collection of the clinical materials, sum up and analyze. If can be according to following the requirement of medical science of card, summarize scientific analysis to a large number of clinical cases, can publish the high-quality scientific paper too, not only can improve one's own clinical ability to work, can also offer the reference experience to others. This is glamour of clinical scientific research.


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